How to Say "genetic makeup" in Spanish
The Spanish word for “genetic makeup” is “genética” — B1 level. This is a very common word in everyday Spanish.
English → SpanishB1
nounB1
referring to a person's specific traits

Examples
La genética es una rama fascinante de la biología.
Genetics is a fascinating branch of biology.
Su buena salud se debe en gran parte a su genética.
Their good health is largely due to their genetics.
Always Feminine
When talking about the science, this word is always feminine. You should always use 'la' or 'una' with it.
Science vs. Adjective
Mistake: “El genética es difícil.”
Correction: La genética es difícil.
Related Translations
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