How to Say "one-sided conversation" in Spanish
The Spanish word for “one-sided conversation” is “monólogo” — B1 level. This is a very common word in everyday Spanish.

Examples
El actor se ganó al público con un monólogo impresionante.
The actor won over the audience with an impressive monologue.
Esta noche vamos al club para ver un monólogo de mi cómico favorito.
Tonight we are going to the club to see a stand-up routine by my favorite comedian.
Nuestra cena fue un monólogo; ella no paró de hablar de su gato.
Our dinner was a one-sided conversation; she didn't stop talking about her cat.
Always Masculine
Even though it ends in 'o', it's helpful to remember it always uses masculine articles: 'el monólogo' or 'un monólogo'.
The Stress is Key
The accent mark on the second 'o' (nó) tells you to emphasize that syllable. If you don't, it might be hard for locals to understand you!
Confusing 'Monólogo' with 'Stand-up'
Mistake: “Using the English word 'stand-up' in a Spanish sentence.”
Correction: While some people might understand 'stand-up', the natural way to say it in Spanish-speaking countries (especially Spain) is 'un monólogo'.
Related Translations
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