How to Say "screw it" in Spanish
The Spanish word for “screw it” is “cógelo” — C2 level. This is a very common word in everyday Spanish.
English → SpanishC2
Verb (Compound Command)C2slang
Highly informal and aggressive dismissal of a situation.

Examples
¡Cógelo! (Context: A very angry person dismissing a problem.)
F*** it! / Screw it!
Si el carro no arranca, que el mecánico cógelo.
If the car won't start, let the mechanic fix it (sexual connotation). (Note: This is grammatically awkward but illustrates the meaning.)
The Danger of Coger
The verb 'coger' has a completely different, highly vulgar meaning in most of Latin America compared to Spain. Even if you mean 'take it,' using 'cógelo' in these regions will be understood as a crude sexual command.
Learn Spanish with Inklingo
Interactive stories, personalized learning, and more.