How to Say "sick of" in Spanish
The most common Spanish word for “sick of” is “cansado” — use 'cansado/a' when you are intensely bored or annoyed with a situation or person, often implying a feeling of exhaustion from it. It's a common, informal way to express being fed up..
cansado
cahn-SAH-doh/kanˈsaðo/

Examples
Estoy muy cansado de tus excusas.
I'm very sick of your excuses.
Estoy cansado de que siempre llegues tarde.
I am fed up with you always arriving late.
El público estaba cansado de las promesas vacías del político.
The public was tired of the politician's empty promises.
The Necessary 'De'
When 'cansado' means 'fed up' or 'tired of,' you must place the small word 'de' (of/from) immediately after it, followed by the thing, person, or action causing the fatigue.
Forgetting the Connecting Word
Mistake: “Estoy cansado escuchar esto.”
Correction: Estoy cansado **de** escuchar esto. You need 'de' to link the feeling to the source of annoyance.
harta
AR-tah/ˈaɾta/

Examples
¡Ya estoy harta de esperar!
I'm fed up with waiting!
Estoy harta de esperar. ¡Vámonos ya!
I am fed up with waiting. Let's go already!
Ella está harta de escuchar siempre las mismas excusas.
She is sick of always hearing the same excuses.
Using 'Estar'
Use the verb estar (to be, for states) with harta to describe the temporary state of being fed up, not ser (to be, for permanent traits).
Missing the Connector
Mistake: “Estoy harta con mi trabajo.”
Correction: Estoy harta de mi trabajo. (Always use *de* to connect 'harta' to the thing causing the frustration.)
Choosing between 'cansado' and 'harto'
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