How to Say "vaccine" in Spanish
The Spanish word for “vaccine” is “vacuna” — A2 level. This is a very common word in everyday Spanish.
English → SpanishA2
nounA2
medical substance

Examples
La vacuna contra la gripe es anual.
The flu vaccine is annual.
Mañana me ponen la segunda vacuna.
I am getting the second shot tomorrow.
Gender and Articles
Since this word ends in '-a' and is feminine, always use 'la' or 'una' before it.
Vaccine vs. Cow
Mistake: “Confusing 'vacuna' with 'vaca'.”
Correction: While related historically, 'vaca' is the animal (cow) and 'vacuna' is the medicine (vaccine).
Related Translations
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