How to Say "tired of" in Spanish
The Spanish word for “tired of” is “harto” — B1 level. This is a very common word in everyday Spanish.

Examples
Estoy harta de escuchar la misma canción en la radio.
I'm fed up with hearing the same song on the radio.
Mis vecinos están hartos de las fiestas ruidosas.
My neighbors are sick and tired of the noisy parties.
Dile que ya estamos hartos de sus excusas.
Tell him we are tired of his excuses.
Using 'Estar'
This adjective usually pairs with the verb 'estar' (to be, for temporary states) because being 'fed up' is a feeling or condition, not a permanent characteristic.
Agreement and Gender
'Harto' changes its ending to match the person or people feeling the emotion: 'harto' (M, singular), 'harta' (F, singular), 'hartos' (M/mixed, plural), 'hartas' (F, plural).
Missing the Preposition
Mistake: “Estoy harto la situación.”
Correction: Estoy harto **de** la situación. (You need 'de'—meaning 'of' or 'with'—to introduce the thing causing the annoyance.)
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